Programme

Tuesday 24.4.2018

9:00-10:00 Registration and coffee
10:00-10:15 Opening of the symposium
Peptide-Based Drugs
10:15-11:00 Cell Penetrating Peptides: Penetrating the Impenetrable Dr Sarah Jones, University of Wolverhampton, UK
11:00-11:45 Turning affibody molecules into efficient peptide binders by dimerization Prof John Löfblom, KTH Royal Institute of Technology, Sweden
Oral presentations selected from abstracts (all topics)
11:45-12:00 Identification of novel selective trypsin-3 inhibitors to prevent prostate cancer cell invasion Muhammad Ahmed, University of Helsinki, Finland
12:00-12:15 Targeting the pathogenic interactions of a Staphylococcus aureus toxin to combat severe infections Prof Outi Salo-Ahen, Åbo Akademi University, Finland
12:15-12:30 Nitrous oxide exposure evokes rebound slow EEG oscillations and molecular changes linked to rapid antidepressant action Samuel Kohtala, University of Helsinki, Finland
12:30-13:30 Lunch
The Finnish Pharmacological Society 70 years Symposium Part I:
Eicosanoids and TRP channels – targets for new therapies
13:30-14:15 Drug Development Perspectives: From New NSAIDs to Novel Prostacyclins Honorary Member Prof Brendan Whittle, Queen Mary University of London, UK
14:15-15:00 TRPA1: A Novel Anti-Inflammatory Target Prof Eeva Moilanen, University of Tampere, Finland
15:00-15:30 Anti-inflammatory properties of TRPA1 antagonists. Pyrazine-fused triterpenoids as an example Dr Ilari Mäki-Opas, University of Tampere, Finland
15:30-15:45 Coffee and refreshments (available also during poster session)
Poster session (all topics)
15:45-ca 17:00 3 min poster presentations in the auditorium (separate schedule), no poster boards for paper posters will be available
ca 17:00-18:00 Society meetings (members only)
19:00-22:00 Dinner (at Hotel Rantapuisto)
FPS 70th Anniversary Banquet
Dress code: Dark suit (recommended)

Wednesday 25.4.2018

Medicinal Chemistry
9:00-9:45 Development of p38α MAP Kinase Inhibitors Prof Stefan Laufer, University of Tübingen, Germany
9:45-10:30 In Silico Discovery of Small Molecule Ligands with Tailored Affinity and Efficacy Profiles Prof Peter Kolb, Philipps-University Marburg, Germany
10:30-11:00 Coffee
11:00-11:30 The Impact of Prolyl Oligopeptidase Inhibitors on Alpha-Synuclein Aggregation Dr Timo Myöhänen, University of Helsinki, Finland
Oral presentations selected from abstracts (all topics)
11:30-11:45 Photoaffinity labeling approach towards binding site identification of chroman-4-one based sirtuin 2 inhibitors Dr Tina Seifert, University of Gothenburg, Sweden
11:45-12:00 Azulene-based compounds as OX1 and OX2 orexin receptor ligands Ainoleena Turku, University of Helsinki, Finland
12:00-12:15 Widespread Regulation of Gene Expression by Glucocorticoids in Chondrocytes from OA Patients as Determined by Next Generation Sequencing-Based Genome Wide Expression Analysis Antti Pemmari, University of Tampere, Finland
12:15-12:30 Drug Discovery and Chemical Biology Network (DDCB) – national infrastructure for drug discovery and chemical biology research in Finland Dr Päivi Tammela, Centre for Drug Research, University of Helsinki
12:30-13:30 Lunch
Finnish Pharmacological Society 70 yrs Symposium Part II:
GPCRs as Drug Targets
13:30-14.00 Honorary Member, Nobel Prize laureate Prof Brian K. Kobilka and his work on GPCRs Prof Mika Scheinin, University of Turku, Finland
14.00-14:45 Human Drug Targets: Trends in GPCR Drug Discovery Prof Helgi Schiöth, Uppsala University, Sweden
14:45-15:15 The story of ORM-12741: A Selective alpha2C Receptor Antagonist Dr Juha Rouru, Orion Pharma, Finland
15:15-15:30 Closing remarks of the symposium